Various tests are done to confirm hormonal imbalance and to check for complications arising out of them. The doctor may call for blood tests to check for thyroid, estrogen, testosterone, and cortisol levels. A Pap smear will be used to check for unusual lumps, cysts, or tumors while an ultrasound will be used to get images of the uterus, ovaries, thyroid, and pituitary glands. A biopsy will be done if the tumor is suspected, while an MRI or X-ray will look for bone loss.

Treatment options are wide and varied. Estrogen therapy, vaginal estrogen, hormonal birth control, and anti-androgen medications aim to balance the sex hormones. Thyroid hormone therapy and drugs such as Levothyroxine are given to address thyroid issues, while drugs such as Metformin, Flibanserin, bremelanotide, and Eflornithine are given to address various consequences or complications arising out of hormonal imbalance. IVF techniques and drugs such as Clomiphene and letrozole are given to women with PCOS who are trying to conceive.

In addition to the above, friends and family may suggest native medicine or alternate treatments. However, these should be pursued with caution as there is no documentary evidence on their efficacy or side effects.